Exomiser error " Exception in thread "main" java.lang.OutOfMemoryError: Java heap space "
Exomiser error " Exception in thread "main" java.lang.OutOfMemoryError: Java heap space " full line is " 2017-07-04 02:34:52.617 [main] INFO de.charite.compbio.exomiser.core.factories.VariantFactory - Processed 325375 variant records into 326224 single allele variants, 989 are missing annotations, most likely due to non-numeric chromosome designations " solution is, u have to increase java heap size like this before change, it was -Xms2g -Xmx4g and now after change -Xms4g -Xmx10g