drug design, and other medical databases and tools

ANTIMIC -- A Database of Antimicrobial Peptides Sequences

Search for sequence and other information of known and putative antimicrobial peptides (AMPs).

APD2 -- the Antimicrobial Peptide Database

Search for detailed information on antimicrobial peptides.

AngioDB -- database of angiogenesis and angiogenesis-related molecules

Search for information about angiogenesis and angiogenesis-related molecules.

BSD -- the Biodegradative Strain Database

Search for detailed information on degradative bacteria and the hazardous substances that they degrade.

BindingDB -- a web-accessible database of experimentally determined proteinx96ligand binding affinities

Search for published protein-ligand binding affinity data.

BioDrugScreen -- Docking Resource for Structure-Based Computational Drug Design

Perform drug discovery based on docking structure.

Biobanks -- transnational, European and global networks

A key resource in unravelling the association between disease subtypes and small, but systematic, variations in genotype, phenotype, and lifestyle.

CAMP -- Collection of Anti-Microbial Peptides

Find information about antimicrobial peptides (AMPs) as better substitutes to antibiotics.

CYCLONET x97 an integrated database on cell cycle regulation and carcinogenesis

Search information on cell cycle regulation in mammals in normal and pathological states

DART -- Drug adverse reaction target database

Search for information on documented adverse reaction targets, functions and properties.

DITOP -- Drug-induced toxicity related protein database

Provides comprehensive information of drug-induced toxicity related proteins.

DrugBank -- a comprehensive resource for in silico drug discovery and exploration

Combines detailed drug data with comprehensive drug target and drug action information.

DrugViz -- a Cytoscape plugin for visualizing and analyzing small molecule drugs in biological networks

Analyze data from chemogenomics, metabolomics and systems biology.

FAF-Drugs -- free ADME/tox filtering of compound collections

Process compound collections via simple ADME/Tox filtering rules.

GLIDA -- GPCR-ligand database for chemical genomic drug discovery

Search for information on G-protein coupled receptors (GPCRs) and their known ligands.

Gene Review

Search for online publication of expert-authored disease reviews

Geno2pheno -- estimating phenotypic drug resistance from HIV-1 genotypes

Predict phenotypic resistance of the respective virus to 17 antiretroviral drugs.

HIT -- Herbal Ingredients' Targets database

Find information about the protein targets of herbal compounds.

KEGG PATHWAY Database

Search a collection of pathway maps on metabolism, signal transduction, gene regulation, and cellular processes.

MATADOR -- Manually Annotated Targets and Drugs Online Resource

Resource for protein-chemical interactions.

MEDock -- a web server for efficient prediction of ligand binding sites based on a novel optimization algorithm

Predict ligand binding sites in protein molecules with a Maximum-Entropy based docking Web server.

MICAD -- The Molecular Imaging and Contrast Agent Database

Provides freely accessible online scientific information on in vivo molecular imaging and contrast agents.

MetaRouter -- bioinformatics for bioremediation

Search for information related to bioremediation and biodegradation.

NAPROC-13 -- search tools to find out the structure of a compound

A database for the dereplication of natural product mixtures in bioassay-guided protocols.

NIH AIDS Research and Reference Reagent Program

Search information on biological and chemical materials for study chemical materials for study of HIV and related opportunistic infections.

NORINE -- a database of nonribosomal peptides

Database entirely dedicated to nonribosomal peptides (NRPs).

PDSP (Psychoactive Drug Screening Program) Drug Database

Search for Ki values (affinity constants) for a large number of G-protein coupled receptors (GPCR's), transporters, and ion channels.

PK/DB -- pharmacokinetic properties database

Database for pharmacokinetic properties and predictive in silico ADME models.

PROMISCUOUS -- Comprehensive Drug-Repositioning Database

Find information about drugs, proteins and side effects.

PharmGED -- Pharmacogenetic Effect Database

Search for information about the effects of a particular protein polymorphism, non-coding region mutation, splicing alteration, or expression variation on the response of a particular drug.

PharmGED -- Pharmacogenetic Effect Database

Search for information about the effects of a particular protein polymorphism, non-coding region mutation, splicing alteration, or expression variation on the response of a particular drug.

PharmGKB -- The pharmacogenetics and pharmacogenomics knowledge base

Search for information about how variation in human genes leads to variation in response to drugs.

PharmaGist -- a webserver for ligand-based pharmacophore detection

Predict molecular interactions for drug design.

Quadbase -- a database of quadruplex motifs

Genome-wide database of G4 DNA--occurrence and conservation in human, chimpanzee, mouse and rat promoters and 146 microbes

STITCH -- search tool for interactions of chemicals

Integrates information about interactions from metabolic pathways, crystal structures, binding experiments and drug-target relationships.

SePreSA -- SErver for the PREdiction of populations susceptible to Serious Adverse drug reaction

Find information about populations carrying polymorphisms within protein binding pockets that make them susceptible to serious adverse drug reaction (SADR).

SuperDrug -- 2D and 3D chemical structures of various drugs

Search for 2D and 3D chemical structures of various drugs.

SuperNatural -- a searchable database of available natural compounds

Search for 50000 natural compounds from different suppliers.

SuperPred -- target-prediction server

Drug classification and target prediction.

SuperTarget -- integrates drug-related information

Find information about drugs.

SuperToxic -- a comprehensive database of toxic compounds

A collection of toxic compounds from literature and web sources.

T3DB -- Toxin and Toxin-Target Database

Find biological, chemical and mechanistic information about clinically relevant, commonly encountered or important toxins.

TTD -- Therapeutic Target Database

Search for information about known therapeutic protein and nucleic acid targets, the targeted disease conditions, the pathway information and the corresponding drugs/ligands.

TarFisDock -- a web server for identifying drug targets with docking approach

Identify drug targets using docking approach.

The Connectivity Map -- Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease

Use gene expression profiles to discover functional connections among diseases, genetic perturbation, and drug action.

The HIV positive selection mutation database

Search for selection pressure maps of HIV mutation caused by HIV protease/reverse transcriptase.

The MetaFMF website -- A high quality tool for meta-analysis of FMF

Search for unified data on phenotypex96genotype correlation in familial Mediterranean fever (FMF).

The Peptaibol Database -- A Database for Sequences and Structures of Naturally Occurring Peptaibols

Search for sequence and structure information of natural peptaibols.

The bioinformatics resource for oral pathogens

Search for comprehensive information on molecular biology of oral pathogens.

e-LEA3D -- Drug Design Server

Perform computer-aided drug design based on molecular fragments.